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C., Luo, H

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Single-cell transcriptomics revealed a skin-imprinted trajectory of inflammatory eosinophils that strongly expressed the glucose transporter Slc2a3 (GLUT3) These eosinophils impeded the function of Th1 cells by forming a competitive metabolic niche through preferential glucose uptake

CYP3A4 is mainly involved in the metabolism of chemotherapy drugs to interfere with tumor progression

Metabolism of non-transferrin bound iron produces reactive oxygen species that contributes to the cellular dysfunction and apoptosis of enterocytes [53] and results in damage to the TJ complexes and leakage of LPS and (1 3)--d-glucan (BG), a major component of the fungal cell wall into the circulation [54]