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*Correspondence: Xiufei Gao, [email protected] These authors have contributed equally to this work Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Reduced concentrations of 2-oxoglutarate and acetoacetate along with an upregulation of creatinine, pyruvic acid, glycerophosphocholine and serine emerged as biochemical blood signatures in PD patients

The highest DALY rates per 100,000 population were seen in Honduras (8.85