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George B, You Y, Viswanathan C, Wen S, Baladandayuthapani V, Overman MJ, Kee BK, Kopetz S , Eng C, Garrett CR

PROTAC 24 with the longer PEG-based linker (23 atoms) showed remarkable UPS-dependent degradation potency with DC 50 values of 0.20 M (48 h) and 0.05 (72 h)