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Numerous completed and on-going, independent clinical trials, with a combined [and growing] total of more than 4,000 study participants, have confirmed our belief that VLN tobacco cigarettes drastically reduce smokers exposure to nicotine and effectively reduce the harm caused by smoking. In addition to its VLN cigarettes, 22nd Century also produces Moonlight, a low tar-to-nicotine cigarette which contains tobacco with relatively high nicotine while at the same time yielding very low tar levels per unit of nicotine