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In fact, one of the key changes in physiology associated with longevity is an increased acetylation of mitochondrial proteins [9]

Sudbury, Massachusetts: Jones and Bartlett Publishers

The observed effects simply cease when supplementation is stopped

Planta 133:2125 Foyer CH, Lelandais M, Galap C, Kunert KJ (1991) Effects of elevated cytosolic glutathione reductase activity on the cellular glutathione pool and photosynthesis in leaves under normal and stress conditions