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GLP-1 therapy's side effects are predominantly gastrointestinal (nausea, occasional vomiting, constipation), with secondary effects on heart rate and theoretical concerns about pancreatitis and gallbladder disease

Emerging/Translational Insights Metabolic health targets

Patients receiving long-term therapy with omeprazole or other proton pump inhibitors (PPIs) should be monitored for signs of B12deficiency

But heres the thing we havent touched on: some research finds that a B12 deficiency can also result in weight gain

I dropped from 186 pounds to around 163, my appetite was almost nonexistent, and I felt sharper than I had in years