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The findings of the rapid and long-lasting antidepressant effects of LAC (which increases the expression of mGlu2, inhibitor of spontaneous glutamate release) supports the idea that targeting the glutamate system can lead to rapid antidepressant effects in agreement with the prior discovery of the antidepressant action of ketamine [48,49,50]

Uno studio di 12 mesi ha osservato una riduzione dellinsufficienza cardiaca e decessi tra i partecipanti che hanno assunto integratori di L-carnitina

L-acetylcarnitine in the treatment of patients with peripheral neuropathies: a short term, double-blind clinical study of 426 patients

Fitting these data to the Hill equation gave an apparent affinity for Na + in the low mM range (8.62 1.8 mM) (Supplementary Table 3), in line with previous studies 6,22,43,44 , with one report indicating a lower apparent K M of 0.3 mM 23 , which may reflect the choice of N -methyl-d-glucamine as a counter-ion versus Cs +

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