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Yes, untreated vitamin B12 deficiency can cause irreversible neurological damage, particularly affecting peripheral nerves and the spinal cord

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The complementary nature of these mechanisms means the combination addresses healing from multiple angles simultaneously

Before using this medication, tell your doctor or pharmacist your medical history, especially of: low potassium blood levels (hypokalemia), gout, a certain blood disorder (polycythemia vera), a certain eye disease (Leber's disease), other vitamin/mineral deficiencies (especially folic acid and iron)

Although typically used doses of licorice are considered safe for most people, those with existing hypertension, kidney disease, or heart disease should use licorice with caution, unless it is deglycyrrhizinated (typically referred to as DGL)