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Finally, NADP + is utilized in the pentose phosphate pathway to regenerate NADPH, which can then be used for nucleotide synthesis [2]

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Among antioxidants, N-acetyl-L-cysteine (NAC) is widely studied and has recently been proposed to have therapeutic benefit in treating AMD by mitigating oxidative damage in the RPE [12]

doi: 10.1073/pnas.0800708105 43 YangJBrownMSLiangGGrishinNVGoldsteinJL

(138) proved that paeoniflorin could significantly improve the symptoms of CIA rats, reduce the levels of pro-inflammatory factors (TNF-, IL-1 and IL-6), and down-regulate the expression of p-NF-B p65 and p-myosin-binding subunit (MYPT1)