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however, the exorbitant expenses of these pharmaceutical agents may restrict their prolonged usage [84]

Seroopidemiology of Helicobacter pylori infection of developing and developed countries

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SOCS2 specifically recognizes the N-terminal domain of SLC7A11 via its src homology 2 (SH2) domain and, using residues L162/C166 in its BOX domain, binds Elongin B/C to form a complex that recruits ubiquitin molecules, facilitating K48-linked polyubiquitination and degradation of SLC7A11