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Note that pregnancy often causes lower histamine levels, and allergies often subside during pregnancy

Therefore, it is essential to thoroughly validate mouse findings in humanized models, like patient-derived iPSC 3D brain organoids, to ensure they are applicable to humans

Down-regulation of a hepatic transporter multidrug resistance-associated protein 2 is involved in alteration of pharmacokinetics of glycyrrhizin and its metabolites in a rat model of chronic liver injury

ABCB4 mutations, involved in PFIC3, ICP, and LPAC syndrome, have mostly missense variants in heterozygosity in patients with late-onset diseases

the individual preparations are preferred when researchers need independent dose-response curves on each compound