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Treat-through designs A trial design wherein participants are randomized at the beginning of treatment and continue in the same treatment assignment through to the end of the study

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I have also learned a few hard-earned lessons along the way: a beautiful lounge does not equal clinical precision

Detailed studies are necessary to determine not only the temporal sequence of molecular events, but also the inter-dependence, cross-talk, and the relative contributions of different mechanisms of acrolein toxicity to the pathogenesis/progression of disease

doi: 10.14218/JCTH.2023.00334