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2021;34(1):e14604

A search strategy will be developed using a combination of medical subheadings words and keywords include: Pre-diabetic State or Pre-diabetic States or state, Pre-diabetic or States, Pre-diabetic or Pre-diabetes and Probiotics or Probiotic or Synbiotics or Synbiotic or Pre-biotics or Pre-biotic. This review will be conducted according to the preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) 2015 statement (32)

Animals were kept on a 12:12 lightdark cycle and provided ad libitum access to water and compositionally balanced normal rat chow following protocols of the Animal Care and Use Committee, College of Pharmacy, King Saud University

10.1016/0041-008x(76)90073-9 33 BttnerS.HabernigL.BroeskampF.RuliD.VogtleF

doi: 10.1038/s41467-020-15694-y 53 MarciniakSJ