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2-(Phenylazo)pyridineplatinum(II) catecholates showing photocytotoxicity, nuclear uptake, and glutathione-triggered ligand release

374 Furthermore, the current immunotherapeutic drugs in clinical trials are presented in Table 1

Preclinical studies have demonstrated that dnEFT, which is applied via a clinical-grade spinal cord stimulator or a custom two-electrode system, induces apoptosis in GBM cells and significantly reduces the tumor burden in vivo

If the plasma level is in the high-risk region of the nomogram, the risk of developing hepatotoxicity is 60% or higher, and antidote therapy is warranted