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In tumor tissue, intermittent blood supply leads to an alternating situation of lack-of-oxygen and reoxygenation, which causes oxidative stress

Garzya G, et al

But for those with certain liver enzyme differences or microbiomes that favor TMA production, the risk is tangible and manageable

These endocrine abnormalities if not treated, culminate to metabolic syndrome development, in which the key pathophysiological components include abdominal fat accumulation, reduced systemic insulin sensitivity, low-grade inflammation, high blood pressure, high blood sugar levels, high triglyceride levels, and low levels of high-density lipoprotein (HDL) cholesterol [2]

Catching up on sleep, such as by sleeping late on weekends, appears to mitigate, though may not completely reverse, some of the negative health effects of sleep loss