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J Crohns Colitis 17(Supplement_1):i41 Lloyd-Price J, Arze C, Ananthakrishnan AN, Schirmer M, Avila-Pacheco J, Poon TW, Andrews E, Ajami NJ, Bonham KS, Brislawn CJ, Casero D, Courtney H, Gonzalez A, Graeber TG, Hall AB, Lake K, Landers CJ, Mallick H, Plichta DR, Prasad M, Rahnavard G, Sauk J, Shungin D, Vzquez-Baeza Y, White RA, Bishai J, Bullock K, Deik A, Dennis C, Kaplan JL, Khalili H, Mciver LJ, Moran CJ, Nguyen L, Pierce KA, Schwager R, Sirota-Madi A, Stevens BW, Tan W, Ten Hoeve JJ, Weingart G, Wilson RG, Yajnik V, Braun J, Denson LA, Jansson JK, Knight R, Kugathasan S, Mcgovern DPB, Petrosino JF, Stappenbeck TS, Winter HS, Clish CB, Franzosa EA, Vlamakis H, Xavier RJ, Huttenhower C, Investigators I (2019) Multi-omics of the gut microbial ecosystem in inflammatory bowel diseases

Works best between a concentration of 5-20% Boosts the skins own collagen production Fades pigmentation and brown spots If used under sunscreen it boosts its UV protection Extremely unstable and oxidizes very easily in presence of light or air Stable in solutions with water only if pH is less than 3.5 or in waterless formulations Vit E + C work in synergy and provide superb photoprotection Ferulic acid doubles the photoprotection effect of Vit C+E and helps to stabilize Vit C Potent Vit

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The most common side effects in the retatrutide group were gastrointestinal symptoms, which were dose-dependent and mostly mild to moderate in severity

However, the mechanism is yet to be determined