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Other studies have also examined low-dose buprenorphine initiation protocols that may not require full agonistopioid bridging

PMID 21593213

The compounds research-only status reflects the absence of completed human clinical trials rather than a determination that it is inherently dangerous a distinction that is important for interpreting its regulatory position accurately

This system achieved 90% to 100% efficiency in precise point mutations, knockout, deletion, and codon saturation mutations of genes such as lacL , srtA , and sdp6 , solving the problems of low recombination efficiency and difficult screening in L