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The liver metabolizes Cycloset via CYP3A4

The liver excretes cholesterol through the bile for elimination into the digestive system, but the compound is recycled there

This review comprehensively examines the central role of gut microbiota in PCOS pathogenesis, including shifts in microbial communities such as bacteria, fungi, and viruses, and their impact on critical metabolites like short-chain fatty acids, bile acids, and tryptophan metabolites, which modulate host metabolism and reproductive function

*Correspondence: Luciana Hannibal [email protected] This article was submitted to Metabolomics, a section of the journal Frontiers in Molecular Biosciences Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

(More information) Available evidence suggests that treatment with intravenous or oral lipoic acid may help reduce symptoms of diabetic peripheral neuropathy