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In the case of tobacco smoking, these active substances are a mixture of aerosol particles that include the pharmacologically active alkaloid nicotine, which stimulates the nicotinic acetylcholine receptors in the brain, and other non-psychoactive chemicals that result from combustion

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Stanford professor Robert Jackler says Juuls actions now should be evaluated in the context of its deal with Altria, because Marlboro is the most popular combustible cigarette brand among underage users

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