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Once the homeostasis of the ER is disrupted, a series of cascading reactions are activated, which are closely related to the occurrence of ferroptosis (Figure 4)

Loading on the peptide affinity column and reloading unbound another four times

Schwartzentruber et al., 2021)

Table 1 Iron metabolism directly regulates lipid metabolism

Normal distributions were applied to all inputs, with the mean obtained from the previous optimisation procedure, and coefficient of variation of 180%