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RSL3 and ERASTIN were dissolved in DMSO to make a 10 mM stock solution and used to treated cells with indicated concentration

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Collectively, the results of this study demonstrate that PDI is an important upstream mediator of chemically-induced, GSH depletion-associated hepatocyte ferroptosis, and inhibition of PDI can effectively prevent such injury both in vitro and in vivo

Figure 6 6 Polyphenols and nutritional aspects Research indicates that the intake of polyphenol-rich foods can promote health, chiefly owing to their antioxidant, anti-inflammatory, anticarcinogenic, and several other qualities (499, 500)