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The concentration of CXCL10 was determined by comparing its intensity with that of 0.4 mg/ml BSA

Treatment of these mice with thymulin alleviated fever, reduced apoptosis, increased splenic cell number, and decreased cytokine production, Hsp72, Hsp90, and TLR4 expression, and the activity of the signaling pathways examined

Funding The DelGiorno laboratory is supported by the Vanderbilt-Ingram Cancer Center Support Grant (NIH/NCI 5P30 CA068485), the Vanderbilt-Ingram Cancer Center SPORE in Gastrointestinal Cancer (NIH/NCI 5P50 CA236733), a Vanderbilt Digestive Disease Research Center Pilot and Feasibility Grant (NIH/NIDDK 5P30 DK058404), an American Gastroenterological Association Research Scholar Award (AGA2021-13-02), NIH/NIGMS 1R35 GM142709, and the Sky Foundation, Inc

Moreover, reconstitution of IL-17 expression in intestinal epithelial cells restored susceptibility to develop CNS autoimmunity in mice (19)

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