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PMID: 32809533

[DOI] [PubMed] [Google Scholar] 55.Della Torre S

In rats with acute myocardial ischemiareperfusion injury, elevated plasma Hcy induced mitochondrial dysfunction and oxidative stress through increased cytochrome c release, stimulation of ROS production, and ERK1/2 signaling pathway that subsequently caused cardiac dysfunction [66]

NAM also promoted glutathione biosynthesis

Switching GLP-1 medications is a conversation for your prescribing provider, but tirzepatide represents an option worth discussing if muscle preservation is a primary concern