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Network construction was performed by first creating a matrix of pairwise correlations between all pairs of genes across the measured samples

Maizels RM, Bundy DA, Selkirk ME, Smith DF, Anderson RM

proposed that glycolytic capacity, fatty acid oxidation, and mitochondrial respiratory activity are all impaired in the citrindeficient cells, whilst proteins and genes involved in lipogenesis, cholesterol, and bile acid metabolism are upregulated

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For instance, Olas et al