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References: Yin et al., Metabolism, 2008 Lan et al., J Clin Endocrinol Metab, 2015 Guo et al., Front Pharmacol, 2021 (meta-analysis) Chaudhary et al., Int J Basic Clin Pharmacol, 2023 ADA Standards of Care in Diabetes, 2024 Read more: To view or add a comment, sign in Check out our new chapter in Methods in Enzymology on inhibition of sterol protein function

While generally considered safe, some people may experience side effects such as headaches, dizziness, or stomach upset

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Upon blocking this system by the synthetic small-molecule erastin the import of cysteine is prevented

(28) demonstrated that genistein enhances the endurance of upper airway muscles and mitigates airway collapse by down-regulating the expression of HIF-1 in the genioglossus of CIH rats