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The BBB separates the blood and the brain interstitial fluid (ISF, also referred to extracellular fluid, ECF), and it is a key player in drug delivery to the brain (Fig

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Ciltacabtagene autoleucel, a B-cell maturation antigen-directed chimeric antigen receptor T-cell therapy in patients with relapsed or refractory multiple myeloma (CARTITUDE-1): a phase 1b/2 open-label study

But undeniably, those results were influenced by numerous factors, including variations in study methodologies, sample size, exposure assessment accuracy, and pathogenic complexity

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