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Embodiment 20 The antibody of embodiment 11, wherein said antibody contains at least one heavy chain variable region of an M25DS antibody

doi:10.1016/j.clnu.2016.06.014

Collectively, these findings demonstrate that CMH@lip@Res-TCeO 2 protects neutrophils by potently inhibiting the ROS/mTOR/HIF-1 signaling axis, reducing both intracellular and mitochondrial ROS, mitigating oxidative stress, and preventing apoptosis

Conversely, a smaller safety margin has been reported in some dog species, young animals, and species with a limited production of P-glycoprotein-mediated drug efflux, with neurotoxicity developing at relatively low levels of exposure

The mechanism goes in multiple directions