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NRF1 binds to palindromic recognition sequences in target gene promoters as a homodimer, functioning as a potent transcriptional activator

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For more pronounced changes, such as significant skin brightening and the fading of hyperpigmentation, consistent treatment over three to six months is often required

Another potential candidate would be the use of oxygenation/oxidizing agents such as chlorine dioxide (ClO 2 ), a gas that is readily dissolved in water and derived from its prodrug sodium chlorite (NaClO 2 ) (Andrs et al., 2022), that has been examined for their ability to penetrate biofilms and to target pathogenic microbes (Behnke and Camper, 2012)

Chnh v th, bn nn kin tr s dng hot cht ny ng cch v ng liu lng chun khuyn ngh