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In AD patients, several oxysterols including 27-OHC, 25-OHC, 7, OHC, 7-KC, 7-OHC, 5,6-epoxycholesterol, 5,6-epoxycholesterol, 4-OHC and 4-OHC were increased in frontal and occipital cortex, coincided with an increased expression of pro-inflammatory markers such as IL-1, IL-6, CCL2, MMP-9, and IL-8 (Testa et al., 2016)

In this review article, the authors have provided a detailed overview of these strategies

In addition to mechlorethamine, these include cyclophosphamide, ifosfamide, melphalan, chlorambucil, and bendamustine, which are shown in Figure 2

Its importance has produced a crowded supplement market filled with competing claims about absorption, detoxification and longevity