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Wark PAB, 2026, Organoid Guided N-of-1 (ORIGIN-1) Clinical Trial: A phase 4 study to investigate if people with cystic fibrosis with rare non-F508del CFTR mutations with an in-vitro response to Elexacaftor/ Tezacaftor/ Ivacaftor have a clinically meaningful response to Elexacaftor/ Tezacaftor/ Ivacaftor versus placebo., Preprints | 2025 Chan C

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In a human study of 114 patients under warfarin, after 6 months of treatment with warfarin, no significant variation in plasma vitamin B12 levels could be seen [287]

10.1016/B978-0-12-397153-1.00005-6 25 BalakrishnanR.VijayrajaD.JoS

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