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Glutamine-derived -ketoglutarate is oxidized into oxaloacetate to maintain the production of citrate

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Lee HY, Lee JH, Kim SH, Jo SY, Min KJ

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Finally, this pathway also modulates the tumor immune microenvironment through metabolic reprogramming, as illustrated in Figure 1

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doi: 10.1016/j.neuint.2012.11.009 62 MashimaR.OkuyamaT

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58,59 Overall, the future research direction of GLP-1RAs involves making them more similar to those in the human body, extending their duration of action, and creating oral formulations for easier administration

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