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Moreover, high concentrations of specific vitamins (like vitamin C) cannot be attained orally because absorption rates plateau, and excess is excreted

Second, as an observational study, causality cannot be established, and the findings remain susceptible to residual confounding from unmeasured factors, including confounding by indication, disease severity, prescribing preferences, and lifestyle factors such as diet, physical activity, or cognitive engagement

It is characterized by significant and selective degeneration of dopaminergic neurons in the nigrostriatal pathway

Lifespan extension by peroxidase/dual oxidase-mediated ROS signaling through pyrroloquinoline quinone in C

A major advance would be the ability to fabricate compartments ex vivo and deliver them into cells to stably function as designer synthetic hubs or organelles