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Compatibility of selected critical care drugs during simulated Y-site administration

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The triangle of death in alzheimers disease brain: the aberrant cross-talk among energy metabolism, mammalian target of rapamycin signaling, and protein homeostasis revealed by redox proteomics

Since it is well known that GSH depletion leads to the upregulation of antioxidant genes, many of which are under Nrf2 control and, that in several types of tumors, Nrf2 is constitutively activated [122, 123], a new and indirect approach for cancer therapy may be used to modulate the Nrf2-ARE pathway

NRF2 serves as a key therapeutic target for diabetic nephropathy via ferroptosis inhibition, exhibiting downregulated expression in diabetic models