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Since norfluoxetine is an active metabolite, such association may impact the response of patients to take fluoxetine as well as implications with increased half-life of this molecule, which is already long, for example, by drug bioaccumulation and the ability to induce serotonin syndromes

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However, the real strength of these techniques remains in their ability to unravel complex dynamic interactions between smoke components and cigarette design features

The study included 47 SLT-users and 44 non-users providing a spectrum of pathophysiological, clinico-biochemical, antioxidant parameters, cell cycle progression study of PBMC and morphological changes of red blood cells (RBC)