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Despite all the advantages of a NPs mediated therapy for the treatment of pulmonary disease, it is worth to highlight that the development of NPs formulations suitable for administration to the lungs by inhalation is not straightforward due to the complexity of lung anatomy and physiology and to NPs deposition mechanisms

This section is offered to provide clinicians and patients with a framework and strategy for determining optimal treatment approaches (see Figure 1)

More specifically, activation of ERK/MAPK pathway stimulates the release of molecules such as (a) CREB (Cao et al., 2008) and (b) mammalian target of rapamycin (Hay and Sonenberg, 2004)

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Available at: Autism and Exercise: Special Benefits | Autism Speaks