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Of the 14 cases reviewed, all were taking doses over 1000 mg per day Vitamin B6 deficiency occurred more rapidly from onset of treatment in those taking over 1500 mg per day

Some wellness clinics offer intravenous infusions of vitamins (sometimes called Meyers cocktails) that might be advertised as boutique, concierge, or hang-over cure IV infusions

[DOI] [PMC free article] [PubMed] [Google Scholar] 48.Dinesh D, Lee JS, Scott TM, Tucker KL, Palacios N

Adipose tissue capillaries expand with weight increase and contract with weight decrease

In other words, smaller daily doses are better than infrequent higher ones