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H significantly reduces the release of pro-inflammatory factors, including IL-1 , IL-6, TNF- , NF-B, and HMGB1, while simultaneously increasing the levels of anti-inflammatory factors such as IL-4, IL-10, and IL-13

When the peptide was incubated in the isolated cells as a bound complex with copper and iron molecules, maximal potential was reported

Xu X et al (2024) Biomimetic nano-regulator that induces cuproptosis and lactate-depletion mediated ROS storm for metalloimmunotherapy of clear cell renal cell carcinoma

Structure and post-translational modifications of cluster determinant 36 (CD36)