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The anti-arthritic effect of cardamomin has been evaluated in a rheumatoid arthritis (RA)-induced rat model, specifically on the pain and inflammatory response of RA

GSTs confer xenobiotic adaptation through direct metabolism or sequestration of xenobiotics, and/or indirectly by providing protection against oxidative stress induced by xenobiotic exposure

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In contrast, Th2 (CD4 + IL-4 + ) and Treg cells (CD4 + Foxp3 + ), known to play critical roles counteracting inflammation in arthritis 19,20 , were increased only in the late stages of arthritis (Supplementary Fig