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linked with thyroiditis, type 1 diabetes, Addisons disease and alopecia areata Genetic predisposition a family history and multiple risk genes raise susceptibility Triggers physical injury to skin (Koebner phenomenon), sunburn, or significant stress can precipitate or worsen patches Not caused by diet or hygiene vitiligo is not caused by bad blood, diet or poor hygiene common myths worth dispelling Source: Autoimmune destruction, genetic predisposition, and environmental triggers such as trauma and stress Understand the Root Cause of Vitiligo and Find the Right Solution

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The duration of tranexamic acid therapy should not be shortened due to the high risk of melasma relapse after discontinuation (Kim et al., 2017)

Vitamins C and E: beneficial effects from a mechanistic perspective

Fer-1 and GPX expression can reduce the lipid ROS level and suppress axonal fusion and debris, while ML162 treatments further enhance lipid ROS level, therefore shifting the cells from a status supporting fusion to a status causing debris