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Pkm2 and other key regulators of warburg effect positively correlate with Cd147 (Emmprin) gene expression and predict survival in multiple myeloma

Platinum resistance and sensitive refer to the time-to-relapse within 6 months or after 6 months following completion of platinum-based chemotherapy

10.1016/j.cell.2017.04.004 28 BudanovA

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63 , 64 These observations suggest that a reducing condition in the nucleus proves to be essential in maintaining a stable cell cycle, especially considering the fact that oxidative stress harms lipids, proteins and DNA