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The GLP-1 and GIP components enhance insulin secretion and sensitivity, while the glucagon component, somewhat paradoxically, does not worsen blood sugar control because its glucose-raising effects are offset by the dominant insulin-enhancing effects of the other two pathways

Crystal structure of the tetrameric cytidine deaminase from Bacillus subtilis at 2.0 resolution

Fast-forward through my medical residency at Albert Einstein College of Medicine, when I had a ward rotation on the general clinical research center where I saw a number of these patients