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Because reactive oxygen species (ROS) play key regulatory roles in multiple redox-sensitive signaling cascades, maintaining their concentrations within a physiological range is essential for cellular homeostasis

This crucial step in the synthesis of dopamine is known to be downregulated or reduced in a variety of neurodegenerative disorders, [21] including Alzheimers disease

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If not treated rapidly with NAC, liver failure and death can occur

After treatment with 40100 M KL1, 100 M KL2, 40100 M inactive analogue KL7, 110 M BIX-01294 or 20 M BHA, infected cells were washed twice with 200 l PBS and incubated with 100 l of 2550 M Fl-B in PBS at 37 C for 30 min