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Together, they create a "sparing" effect that helps maintain higher levels of both antioxidants

Low Dose Naltrexone (LDN) is emerging as a promising new off-label treatment for management of symptoms from autoimmune diseases, central nervous system disorders, and even certain cancers

In chronic cases, tophi may develophard uric acid deposits under the skin around joints or ears

144,145 In addition, while current scoring systems can identify mild cases with high accuracy, their ability to predict moderate to severe AP remains limited, with an accuracy of approximately 50%

doi: 10.3389/fphar.2024.1268134 143 ChenCLeiHZhaoYHouYZhengHZhangCet al