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This substantial deacetylation is the reason that high plasma levels of acetyl-l-carnitine are not observed after its oral intake, unlike after parenteral administration, during which the substance bypasses the gut and enters the bloodstream directly

Archives of pharmacal research , 30 (7), 834-839.

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Data reported included all samples analyzed

Ther., 329, 649 (2009), Yu, Y-C., et al.: J