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Normal rabbit IgG (polyclonal antibody, 2729, Cell Signaling Technologies) served as control

Valls-Pedret C, Lamuela-Raventos RM, Medina-Remon A, et al

Deficiency in Mfn1 or Mfn2 expression disrupts mitochondrial structure, promoting cardiomyocyte hypertrophy and heart failure, and significantly inhibiting the expression of mitochondrial biogenesis-related proteins (PGC-1 and Nrf-1) [71]