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Repeated injections in the same site compound trauma to surrounding vessels and increase the likelihood of noticeable discoloration

doi: 10.1073/pnas.2009201117 27 KraftVANBezjianCTPfeifferSRingelstetterLMullerCZandkarimiFet al

Researchers should establish baseline peptide concentrations through analytical testing before initiating experimental protocols to ensure reproducible results across research studies

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If both the reduced and the oxidized form can move a pigment marker, the field does not yet have a settled account of what the active species even is in living skin