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438 Syrosingopine, a clinically approved druge, exhibits anticancer effects on various malignancies, including myeloma, 439 and holds potential as a future adjunct therapy for cancer

71,72 At a pre-clinical level, the protective effects of vitD has been linked to enhanced innate immune production of ROS, IL-1, IFN- and cathelicidin, 73,74 while positive trials have shown a reduction in inflammatory mediators including matrix metalloproteinases (MMPs) (Table 1)

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