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Shore [52] suggests that strategies (probiotics/prebiotics) that alter the gut microbiome or/and its metabolic products, such as dietary manipulations, may represent a new frontier for treating asthma in obese individuals

However, some gout patients with elevated 24-hour urine uric acid, as described in Japanese cohorts, have renal uric overload due to intestinal ABCG2 dysfunction without uric acid overproduction ( Figure 1 - 5 )

Pietrini F, Iori V, Cheremisina A, Shevyakova NI, Radyukina N, Kuznetsov VV, Zacchini M (2015) Evaluation of Ni tolerance in Amaranthus paniculatus L

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Milk Thistle: Milk thistle is an herb that has been used for centuries to support liver function and aid in detoxification