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J Gerontol A Biol Sci Med Sci 61(7):663674 Clavel S, Coldefy AS, Kurkdjian E, Salles J, Margaritis I, Derijard B (2006) Atrophy-related ubiquitin ligases, atrogin-1 and MuRF1 are up-regulated in aged rat Tibialis Anterior muscle

Bone Marrow Transplant 14(3):449-53, 1994

The consequences can be devastating

These cell lines can be used as antigen presenting cells in subsequent experiments using blood from the same donor

This hypoxic and acidic microenvironment in metabolically altered GBMs affects radiotherapy efficacy and drug delivery, and plays a crucial role in biological mechanisms involved in cancer progression and treatment resistance, such as aberrant DNA repair, angiogenesis, and cancer stem cell maintenance [5,6,7,8,9,10]