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The JAK/STAT signaling pathway, as the main target for inhibiting the action of a variety of cytokines (221), is involved in the signal transduction of many key cytokines for the pathogenesis of RA and has been considered as a potential target for the treatment of RA (222)

doi: 10.1007/s00401-012-0954-z 21 BakanSKayadibiYErsenEVatankuluBUstundagNHaslogluZI

However, as the MVD progresses, the dog's ability to produce active BNP declines, lessening its ability to counter the effects of RAAS activation

Results for all cognitive tests are presented in Supplementary Table 2

However, the remaining fat cells can enlarge if significant weight gain occurs, which may affect the overall contour of the arms